Rose’s recent research has focused on identifying trends in poisonings and analysing the effect of drug policy and scheduling. This includes work on daily dosing errors with oral methotrexate, where Rose identified increasing poisonings in recent years, including several deaths. Her work resulted in changes to the manufacturer Product Information and Consumer Medicines Information for methotrexate, and a labelling change. Rose has also examined the effect of medicine up-scheduling on drug use and misuse (recent examples include studies on codeine and alprazolam). There are several opportunities for new projects in this area using poisons centre, dispensing, hospitalisation and coronial data.
Another of Rose’s interests is Poisons Information Centre service utilisation and impact. Australian Poisons Information Centres take calls from members of the public and healthcare professionals and can thus potentially reduce unnecessary hospitalisations, improve management, optimise antidote utilisation and minimise length of stay.
Rose is interested in poisoning epidemiology, in particular she aims to uncover and assess geographical inequalities in poisoning risk and access to life-saving treatments. She aims to identify at-risk groups of paediatric poisoning and deliberate self-poisoning and identify ways to best address health system inequalities and unwarranted clinical variation. There are several opportunities for new projects in these areas which include analysis of linked data.
