Dr. Kartha's research interests are in deciphering the pathophysiological role of oxidative stress in disease conditions such as neurodegenerative disorders and ischemia/reperfusion injury. Her research involves understanding the molecular pharmacology of antioxidants and other drugs used to treat these conditions using cell culture and animal models and identification of novel protein- or miRNA-based biomarkers for early diagnosis of these conditions and as markers of response to therapy using patient derived samples.