Research in the Lurie laboratory focuses on the CNS response to injury and disease, with a particular emphasis on the glial response to injury. Previous work in the Lurie laboratory has focused on the role that tyrosine phosphorylation plays in the signal transduction events that occur following damage to the nervous system, particularly in stroke. In addition, our group has also examined the ways in which low levels of lead exposure modulate the development of sensory systems in the brainstem, with a focus on the developing auditory system.